Hao WuProfessor

Ph.D.

Professor of Fudan University Human Phenome Institute

Email: hao_w@fudan.edu.cn

Lab:https://microbiome.fudan.edu.cn/main.htm



  Work Experience

2002-2006: Department of Life Sciences, Shandong University of Technology;

2007-2012, James D. Watson institute of genome sciences, Zhejiang University;

2012-2014, Beijing Institute of Genomics, Chinese Academy of Sciences;

2015-2020, Sahlgrenska university hospital, University of Gothenburg, Sweden.

 Research Interests

1)Gastrointestinal health and gut microbiota;

2)Microbial dysbiosis and incidence of various cardiometabolic diseases;

3)Diet- and drug- microbiota interactions;

4)Integration of multi-omics datasets;

5)Bacterial genomics and evolution.

Selected Publications

1. Hao Wu*, Valentina Tremaroli*, Caroline Schmidt, Annika Lundqvist, Lisa M Olsson, Manuela Krämer, Anders Gummesson, Rosie Perkins, Göran Bergström#, Fredrik Bäckhed#. The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study. 2020. Cell Metabolism 32 (3), 379-390. e3

2. Ara Koh, Antonio Molinaro, Marcus Ståhlman, Muhammad Tanweer Khan, Caroline Schmidt, Louise Mannerås-Holm, Hao Wu, Alba Carreras, Heeyoon Jeong, Louise E Olofsson, Per-Olof Bergh, Victor Gerdes, Annick Hartstra, Maurits de Brauw, Rosie Perkins, Max Nieuwdorp, Göran Bergström, Fredrik Bäckhed#. Microbially produced imidazole propionate impairs insulin signaling through mTORC1. 2018. Cell 175 (4), 947-961. e17

3. Adil Mardinoglu*, Hao Wu*, Elias Bjornson, Cheng Zhang, Antti Hakkarainen, Sari M Räsänen, Sunjae Lee, Rosellina M Mancina, Mattias Bergentall, Kirsi H Pietiläinen, Sanni Söderlund, Niina Matikainen, Marcus Ståhlman, Per-Olof Bergh, Martin Adiels, Brian D Piening, Marit Granér, Nina Lundbom, Kevin J Williams, Stefano Romeo, Jens Nielsen, Michael Snyder, Mathias Uhlén, Göran Bergström, Rosie Perkins, Hanns-Ulrich Marschall, Fredrik Bäckhed#, Marja-Riitta Taskinen, Jan Borén#. An integrated understanding of the rapid metabolic benefits of a carbohydrate-restricted diet on hepatic steatosis in humans. 2018. Cell metabolism 27 (3), 559-571. e5

4. Hao Wu*, Eduardo Esteve*, Valentina Tremaroli, Muhammad Tanweer Khan, Robert Caesar, Louise Mannerås-Holm, Marcus Ståhlman, Lisa M Olsson, Matteo Serino, Mercè Planas-Fèlix, Gemma Xifra, Josep M Mercader, David Torrents, Rémy Burcelin, Wifredo Ricart, Rosie Perkins, José Manuel Fernàndez-Real#, Fredrik Bäckhed#. Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug. 2017. Nature medicine 23 (7), 850

5. Hao Wu*, Valentina Tremaroli*, Fredrik Bäckhed#. Linking microbiota to human diseases: a systems biology perspective. 2015. Trends in Endocrinology & Metabolism 26 (12), 758-770

6. Hao Wu, Yongjun Fang, Jun Yu#, Zhang Zhang#. The quest for a unified view of bacterial land colonization. 2014. The ISME journal 8 (7), 1358-1369