Shaohua FanProfessor

Professor,Doctoral Supervisor

Email:shaohua_fan@fudan.edu.cn

  Work Experience

Dr. Fan graduated from Northwest Agriculture and Forestry University in 2008 with a master degree in Biochemistry and Molecular Biology, and then got his PhD degree in Evolutionary Biology from the Department of Biology at the University of Konstanz in 2014. After a short period of Postdoc at the University of Konstanz, he moved to the U.S and had his postdoctoral training in Prof. Sarah Tishkoff’s lab at the University of Pennsylvania from 2015 to 2018. In August 2018, Dr. Fan became a PI at the School of Life Sciences and Human Phenome Institute, Fudan University, China.

  Research Interests

1. Demographic history and local adaptation of modern humans.

2. Molecular mechanisms of phenotypic variation.

3. The evolution of structural variation in modern humans.

  Awards

1. 2016 AAAS/Science program for Excellence in Science

2. 2012 Chinese government awards for outstanding self-financed student abroad

3. 2011 Travel grant from Frontiers in Speciation Research for visiting Prof. Yves van de Peer, University of Ghent, Belgium

4. 2009 Doctoral stipend from DAAD

5. 2009 ESF conserve genetics and thermal adaptation, travel grant to Ecological Genomics Workshop, Centro Residenziale Universitario di Bertinoro, Bertinoro (FC), Italy

  Selected Publications

1.Shaohua Fan; Jeffrey P. et al.,  Whole-genome sequencing reveals African population demographic history and signatures of local adaptation, Cell, 2023 (封面文章)

2. Fan, S., Kelly, DE., Beltrame, MH., et al. 2019 African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations.Genome Biology, 20, Article number: 82

3. Crawford, NG., Kelly, DE*., Hansen ,MEB*., Beltrame,MH*., Fan, S* et al. Loci associated with skin pigmentation identified in African populations.Science. (6365), eaan8433. (*Co-second author)

4. Fan, S*., Hansen, ME*., Yancy, L*., Tishkoff, SA, 2016. Going global by adapting local: A review of recent human adaptation.ScienceVol. 354, Issue 6308, pp. 54-59. (Cover article, *co-first author)

5. Lin, Q*.,Fan, S*., et al., 2016. The seahorse genome provides insights into the evolution of its specialized body plan.Nature540, 395–399 doi:10.1038/nature20595. (Cover article, *co-first author)

6. Fan, S., Elmer, K.R. and A. Meyer. 2012. Genomics of adaptation and speciation in cichlid fishes: recent advances and analyses in African and Neotropical lineages.Philosophical Transactions of the Royal SocietyB 367: 385-394.

7. Fan, S., Elmer, K.R. and A. Meyer. 2011. Positive Darwian selection drives the evolution of the morphology-related gene, EPCAM, in particularly species-rich lineages of African cichlid fishes.Journal of Molecular Evolution73: 1-9.