Work Experience
Postdoctoral Research 2021 - Current
Human Phenome Institute, Fudan University
Ph.D. Program 2017 - 2021
School of Medical Sciences, The University of Sydney
Information Technology Capstone Project 2017
School of Computer Science, The University of Sydney
Summer Scholarship Program 2016 - 2017
Bioinformatics Lab, Victor Chang of Cardiac Research Institute
Electrical Engineer 2013 - 2015
Clark Equipment Australia Pty Ltd
Research Interests
1. Developing computational methods and tools to improve structural variant (SV) detection, phasing and interpretation in human genome.
2. Applying cutting-edge genomic technologies and bioinformatics analytics to identify the extent of SV acquired during cancer progression, and determine how these large genomic rearrangements drive disease progression and tumour evolution.
3. The role of structural variation for the diversity and evolution of human genomes.
Awards
1、Office of China Postdoctoral Council (OCPC) International Postdoctoral Program 2021
2、Australian Research Training Program Scholarship 2017 - 2021
3、Dean’s Excellency Award 2016
Selected Publications
1. Gong T, Jaratlerdsiri W, Jiang J, Willet C, Chew T, Patrick SM, Lyons RJ, Haynes A-M, Pasqualim G, Brum IS, et al: Genome-wide interrogation of structural variation reveals novel African-specific prostate cancer oncogenic drivers. Genome Medicine 2022, 14:100.
2. Gong T, Hayes VM, Chan EKF: Detection of somatic structural variants from short-read next-generation sequencing data. Briefings in Bioinformatics 2021, 22:bbaa056.
3. Gong T, Hayes VM, Chan EKF: Shiny-SoSV: A web-based performance calculator for somatic structural variant detection. PLOS ONE 2020, 15:e0238108.
4. Hayes VM, Gong T, Mutambirwa SBA, Jaratlerdsiri W, Bornman MSR: African inclusion in prostate cancer genomic studies provides the first glimpses into addressing health disparities through tailored clinical care. Clin Transl Med 2023, 13:e1142.
5. Jaratlerdsiri W, Jiang J, Gong T, Patrick SM, Willet C, Chew T, Lyons RJ, Haynes A-M, Pasqualim G, Louw M, et al: African-specific molecular taxonomy of prostate cancer. Nature 2022, 609:552-559.
6. Crumbaker M, Chan EKF, Gong T, Corcoran N, Jaratlerdsiri W, Lyons RJ, Haynes AM, Kulidjian AA, Kalsbeek AMF, Petersen DC, et al: The Impact of Whole Genome Data on Therapeutic Decision-Making in Metastatic Prostate Cancer: A Retrospective Analysis. Cancers (Basel) 2020, 12.
7. Jaratlerdsiri W, Chan EKF, Gong T, Petersen DC, Kalsbeek AMF, Venter PA, Stricker PD, Bornman MSR, Hayes VM: Whole Genome Sequencing Reveals Elevated Tumor Mutational Burden and Initiating Driver Mutations in African Men with Treatment-Naive, High-Risk Prostate Cancer. Cancer Research 2018:canres.0254.2018.
