Work Experience
1. B.S., Peking University(1996-2000)
2. Ph.D., Peking University(2000-2006)
3. Postdoc, Duke University(2007-2010)
4. Research Fellow, National Institutes of Health(2010-2012)
5. Professor, School of Life Sciences, Fudan University(2012-present)
Research Interests
Combining genomics, molecular biology, cell biology and bioinformatics tools together to understand how antisense transcription, intron retention and alternative polyadenylation contributes to transcriptome fine-tuning and cellular senescence.
Selected Publications
1.Ni T#, Corcoran DL#, Rach EA, Song S, Spana EP, Gao Y, Ohler U* and Zhu J*. A paired-end sequencing strategy to map the complex landscape of transcription initiation.Nature Methods(Article), 2010; 7: 521-527
2.Ni T#*, Yang W#, Han M#, Zhang Y, Shen T, Nie H, Zhou Z, Dai Y, Yang Y, Liu P, Cui K, Zeng Z, Tian Y, Zhou B, Wei G, Zhao K, Peng W*, Zhu J*. Global intron retention mediated gene regulation during CD4+ T cell activation.Nucleic Acids Research. 2016; 44(14):6817-29
3.Ni T#*, Yang Y#, Hafez D, Yang W, Kiesewetter K, Wakabayashi Y, Ohler U, Peng W and Zhu J*. Distinct polyadenylation landscapes of diverse human tissues revealed by a modified PA-seq strategy.BMC Genomics, 2013; 14(1):615
4. Majerciak V#,Ni T#, Yang W, Meng B, Zhu J* and Zheng ZM* A viral genome landscape of RNA polyadenylation from KSHV latent to lytic Infection.PLOS Pathogens, 2013; 9(11):e1003749
5. Shen T, Li H, Song Y, Yao J, Han M, Yu M, Wei G*,Ni T*. Antisense transcription regulates the expression of sense gene via alternative polyadenylation.Protein Cell, 2017; DOI: 10.1007/s13238-017-0497-0
