Work Experience
1、2018.5- present Associate Professor, Human Phenome Institute, Fudan University
2、2017.12- present Associate Professor, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University
3、2015.5-2017.7 Postdoctoral research fellow, Molecular Neurogenetics Unit, Massachusetts General Hospital, Harvard Medical School
4、2013.12-2017.12 Associate Professor, Institutes of Biomedical Science, Medical School, Fudan University, Shanghai, China
5、2009.3–2013.12 Research Associate, Institute Biomedical Sciences, Medical School, Fudan University, Shanghai, China
Research Interests
1. Genetic etiology of birth defect
2. Genetic mechanism of neurodevelopmental diseases
3. Genotype and Phenotype Correlation
4. Functional Genomics
Selected Publications
1、Guo Ruiji#; Xia Fang#; Hailei Mao; Bin Sun; Jiateng Zhou; Yu An*; Bin Wang*; A Novel Missense Variant of HOXD13 Caused Atypical Synpolydactyly by Impairing the Downstream Gene Expression and Literature Review for Genotype-Phenotype Correlations.,Frontier in Genetics, 2021, 12: 731278.
2、An, Yu*; Zhang, Linna; Liu, Wenwen; Jiang, Yunyun; Chen, Xue; Lan, Xiaoping; Li, Gan; Hang, Qiang; Wang, Jian; Gusella, James F.; Du, Yasong*; Shen, Yiping*; De novo variants in the Helicase-C domain of CHD8 are associated with severe phenotypes including autism, language disability and overgrowth, Human Genetics, 2020, 139: 499-512.
3、Wu, Jing; Yang, Yi; He, You; Li, Qiang; Wang, Xu; Sun, Chengjun; Wang, Lishun; An, Yu*; Luo, Feihong*; EFTUD2 gene deficiency disrupts osteoblast maturation and inhibits chondrocyte differentiation via activation of the p53 signaling pathway, Human Genomics, 2019, 13(1): 63.
4、An, Yu; Duan, Wenyuan; Huang, Guoying; Chen, Xiaoli; Li, Li; Nie, Chenxia; Hou, Jia; Gui, Yonghao; Wu, Yiming; Zhang, Feng; Shen, Yiping; Wu, Bailin*; Wang, Hongyan*; Genome-wide copy number variant analysis for congenital ventricular septal defects in Chinese Han population, BMC Medical Genomics, 2016, 9: 2.
5、Du, Xiaonan#; An, Yu#; Yu, Lifei; Liu, Renchao; Qin, Yanrong; Guo, Xiaohong; Sun, Daokan; Zhou, Shuizhen; Wu, Bailin; Jiang, Yong-hui*; Wang, Yi*; A genomic copy number variant analysis implicates the MBD5 and HNRNPU genes in Chinese children with infantile spasms and expands the clinical spectrum of 2q23.1 deletion, BMC Medical Genetics, 2014, 15: 62.
