工作经历
2010.2 - 2014.6,澳大利亚新南威尔士大学,电气工程,本科
2012.7 – 2012.12, 美国乔治亚理工大学,国际交流生项目
2016.6 – 2017.6, 澳大利亚悉尼大学,数据科学,硕士
2016.11 – 2017.7, 澳大利亚Victor Chang Cardiac Research Institute, 实习生
2017.8 – 2021.8, 澳大利亚悉尼大学,计算生物学,博士
研究方向
1. 通过开发和改进结构变异检测和解析的方法, 深入了解基因组结构变异的种类和分布, 致力于完善人类基因组结构变异数据库。
2. 运用计算生物学手段,研究体细胞结构变异对癌症(前列腺癌、肺腺癌) 的产生、发展和预后的影响。
3. 运用计算生物学手段,探究结构变异对人类基因组多样性和进化的影响。
获奖情况
博士后国际交流计划引进项目 (2021)
澳大利亚国家研究奖(Australian Research Training Program Scholarship) (2017-2021)
澳大利亚悉尼大学院长杰出奖 (Dean’s Excellency Award) (2016)
代表论文
1. Gong T, Jaratlerdsiri W, Jiang J, Willet C, Chew T, Patrick SM, Lyons RJ, Haynes A-M, Pasqualim G, Brum IS, et al: Genome-wide interrogation of structural variation reveals novel African-specific prostate cancer oncogenic drivers. Genome Medicine 2022, 14:100.
2. Gong T, Hayes VM, Chan EKF: Detection of somatic structural variants from short-read next-generation sequencing data. Briefings in Bioinformatics 2021, 22:bbaa056.
3. Gong T, Hayes VM, Chan EKF: Shiny-SoSV: A web-based performance calculator for somatic structural variant detection. PLOS ONE 2020, 15:e0238108.
4. Hayes VM, Gong T, Mutambirwa SBA, Jaratlerdsiri W, Bornman MSR: African inclusion in prostate cancer genomic studies provides the first glimpses into addressing health disparities through tailored clinical care. Clin Transl Med 2023, 13:e1142.
5. Jaratlerdsiri W, Jiang J, Gong T, Patrick SM, Willet C, Chew T, Lyons RJ, Haynes A-M, Pasqualim G, Louw M, et al: African-specific molecular taxonomy of prostate cancer. Nature 2022, 609:552-559.
6. Crumbaker M, Chan EKF, Gong T, Corcoran N, Jaratlerdsiri W, Lyons RJ, Haynes AM, Kulidjian AA, Kalsbeek AMF, Petersen DC, et al: The Impact of Whole Genome Data on Therapeutic Decision-Making in Metastatic Prostate Cancer: A Retrospective Analysis. Cancers (Basel) 2020, 12.
7. Jaratlerdsiri W, Chan EKF, Gong T, Petersen DC, Kalsbeek AMF, Venter PA, Stricker PD, Bornman MSR, Hayes VM: Whole Genome Sequencing Reveals Elevated Tumor Mutational Burden and Initiating Driver Mutations in African Men with Treatment-Naive, High-Risk Prostate Cancer. Cancer Research 2018:canres.0254.2018.