工作经历
1988及1991年分获复旦大学生物系学士及硕士学位，1999年获日本福井大学生物应用化学专业博士学位。2007-2008年于美国德克萨斯大学休斯顿健康科学中心访问研究。1991-1994年任复旦大学生命科学学院助教、讲师。2000起任复旦大学生命科学学院讲师、副教授、教授。
研究方向
1）硬皮病、强直性脊柱炎等风湿免疫性疾病的遗传学及分子致病机理研究，2）皮肤老化、皮肤晒黑、及皮肤微生态等皮肤表型组学研究。其领导的实验室是国际硬皮病研究的主要实验室，2011年与中美合作者联合发起成立“硬皮病临床与研究国际协作网（InSCAR）”。任Laboratory Investigation、Journal of Scleroderma and Related Disorders等杂志编委。近五年在Blood、Ann Rheum Dis、Microbiome、J Invest Dermatol等发表SCI论文百余篇。
招生专业
遗传学、人类生物学、生物信息学、流行病与卫生统计学、生物与医药
代表论文
1) Shi X, Chen Y, Liu Q, Mei X, Liu J, Tang Y, Luo R, Sun D, Ma Y, Wu W, Tu W, Zhao Y, Xu W, Ke Y, Jiang S, Huang Y, Zhang R, Wang L, Chen Y, Xia J, Pu W, Zhu H, Zuo X, Li Y, Xu J, Gao F, Wei D, Chen J, Yin W, Wang Q, Dai H, Yang L, Guo G, Cui J, Song N, Zou H, Zhao S, Distler JHW, Jin L, Wang J*. LDLR dysfunction induces LDL accumulation and promotes pulmonary fibrosis. Clin Transl Med. 2022 Jan;12(1):e711. doi: 10.1002/ctm2.711. PMID: 35083881.
2) Pu W#, Zhang R#, Ma Y, Liu Q, Jiang S, Liu J, Zhao Y, Tu W, Guo G, Zuo X, Wang Q, Chen Y, Wu W, Zhou X, Distler JHW, Reveille JD, Zou H, Jin L, Mayes MD, Wang J*. Genetic Associations of Non-Major Histocompatibility Complex Susceptibility Loci with Systemic Sclerosis in a Han Chinese Population. J Invest Dermatol. 2021 Dec 15:S0022-202X(21)02614-2. doi: 10.1016/j.jid.2021.11.033. Online ahead of print. PMID: 34919939
3) Pu W#, Wu W#, Liu Q#, Ma Y#, Tu W#, Zuo X#, Guo G#, Jiang S, Zhao Y, Zuo X, Wang Q, Yang L, Xiao R, Chu H, Wang L, Sun L, Cui J, Yu L, Li H, Li Y, Shi Y, Zhang J, Zhang H, Liang M, Chen D, Ding Y, Chen X, Chen Y, Zhang R, Zhao H, Li Y, Qi Q, Bai P, Zhao L, Reveille JD, Mayes MD, Jin L, Lee EB, Zhang X, Xu J*, Zhang Z*, Zhou X*, Zou H*, Wang J*. Exome-wide association analysis suggests LRP2BP as a susceptibility gene for endothelial injury in systemic sclerosis in Han Chinese population. J Invest Dermatol. 2021 May;141(5):1254-1263.e6. doi: 10.1016/j.jid.2020.07.039. Epub 2020 Oct 15. PMID: 33069728
4) Liu J#, Tang Y#, Huang Y#, Gao J, Jiang S, Liu Q, Ma Y, Qian X, Qian F, Reveille JD, He D, Zou H, Jin L, Zhu Q*, Pu W*, Wang J*. Single-cell RNA Sequencing Deciphers Innate Immunity in Pathogenesis and Treatment Response of Ankylosing Spondylitis. Clin Transl Med. 2021 Mar;11(3):e369. doi: 10.1002/ctm2.369. PMID: 33784007
5) Li Z#, Xia J#, Jiang L#, Tan Y#, An Y, Zhu X, Ruan J, Chen Z, Zhen H, Ma Y, Jie Z, Xiao L, Yang H, Wang J, Kristiansen K, Xu X, Jin L, Nie C*, Krutmann J*, Liu X*, Wang J*. Characterization of the human skin resistome and identification of two microbiota cutotypes. Microbiome. 2021 Feb 17;9(1):47.
Full paper: ttps://link.springer.com/content/pdf/10.1186/s40168-020-00995-7.pdf
Video Byte: https://www.researchsquare.com/article/rs-276355/v1.
6) Sun D#, Niu Z#, Zheng H#, Wu F, Jiang L, Han TQ, Wei Y, Wang J*, Jin L*. A mitochondrial DNA variant elevates the risk of gallstone disease by altering mitochondrial function. Cell Mol Gastroenterol Hepatol. 2020 Dec 4:S2352-345X(20)30199-5.
7) Liu J#, Pu W#, Li Y, Ma Y, Zhu Q, Wan W, Yang C, Wang X, Chen X, Zhou X, Reveille JD, Jin L, Zou H*, Wang J*. Genetic association of non-MHC region with ankylosing spondylitis in a Chinese population. Ann Rheum Dis. 2019 Jun;78(6):852-853.
8) Guo S#, Jiang S#, Epperla N, Ma Y, Maadooliat M, Ye Z, Olson B, Wang M, Kitchner T, Joyce J, An P, Wang F, Strenn R, Mazza JJ, Meece JK, Wu W, Jin L, Smith JA, Wang J* and Schrodi SJ*. A gene-based recessive diplotype exome scan discovers FGF6, a novel hepcidin-regulating iron metabolism gene. Blood. 2019Apr 25;133(17):1888-1898.
9) Ding W#, Pu W#, Wang L#, Jiang S, Zhou X, Tu W, Yu L, Zhang J, Guo S, Liu Q, Ma Y, Chen S, Wu W, Reveille J, Zou H, Jin L, Wang J*. Genome-wide DNA methylation analysis in systemic sclerosis reveals hypomethylation of interferon-associated genes in CD4+ and CD8+ T cells. J Invest Dermatol. 2018 May;138(5):1069-1077.
10) Dong Z#, Li Y#, Zhou J, Jiang S, Wang Y, Chen Y, Zhao D, Yang C, Qian Q, Ma Y, He H, Ji H, Yang Y, Wang X, Xu X, Pang Y, Zou H, Jin L, Zhang F*, Wang J*. Copy number variants of ABCF1, IL17REL, and FCGR3A are associated with the risk of gout. Protein Cell. 2017 Jun;8(6):467-470.
