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2. An YP^#, Liu S^#, Hao FH, Wang YL, Tang HR*, Development and Validation of an Improved Probabilistic Quotient Normalization Method for LC/MS- and NMR-Based Metabonomic Analysis. Chinese Chemical Letters 2020, 31(7):1827-1830. doi:10.1016/j.cclet.2019.12.011

3. Chen XD^#, Gole J^#, Gore A^#, He QY^#, Lu M^#, Min J, Yuan ZY, Yang XR, Jiang YF, Zhang TJ, Suo C, Li XJ, Cheng L, Zhang ZH, Niu HY, Li Z, Xie Z, Shi H, Zhang X, Fan M, Wang XF, Yang YJ, Dang J, McConnell C, Zhang J, Wang JC, Yu SZ, Ye WM*, Gao Y*, Zhang K*, Liu R*, Jin L*, Non-Invasive Early Detection of Cancer Four Years before Conventional Diagnosis Using a Blood Test. Nature Communications 2020,11(1):3475. doi:10.1038/s41467-020-17316-z

4. Chen YM^#, Zheng YT^#, Yu Y^#, Wang YZ^#, Huang QX^#, Qian F^#, Sun L^#, Song ZG, Chen ZY, Feng JW, An YP, Yang JC, Su ZQ, Sun SY, Dai FH, Chen QS, Lu QW, Li PC, Ling Y, Yang Z, Tang HR, Shi LM, Jin L, Holmes EC, Ding C*, Zhu TY*, Zhang YZ*, Blood Molecular Markers Associated with COVID-19 Immunopathology and Multi-organ Damage. EMBO Journal 2020, 39(24): e105896. doi:10.15252/embj.2020105896

5. Cui M^#, Jiang YF^#, Zhao QH, Zhu Z, Liang XN, Zhang KX, Wu WQ, Dong Q, An YP, Tang HR, Ding D*, Chen XD*, Metabolomics and Incident Dementia in Older Chinese Adults: The Shanghai Aging Study. Alzheimer’s & Dementia 2020, 16(5):779-788. doi:10.1002/alz.12074

6. Dai Y^#, Tian Q^#, Si J, Sun Z, Shali S, Xu L, Ren D, Chang S, Dong X, Zhao H, Mei Z, Zheng Y*, Ge J B*, Circulating Metabolites from the Choline Pathway and Acute Coronary Syndromes in a Chinese Case-Control Study. Nutrition & Metabolism 2020, 17(1):39. doi:10.1186/s12986-020-00460-0

7. Ding LF^#, Zhang CC, Liu ZG, Huang QX, Zhang YL, Li SP, Nie GJ, Tang HR, Wang YL*, Metabonomic Investigation of Biological Effects of a New Vessel Target Protein tTF-pHLIP in a Mouse Model. Journal of Proteome Research 2020, 19(1):238-247. doi:10.1021/acs.jproteome.9b00507

8. Ding LJ^#, Lian Y, Lin ZZ, Zhang ZY, Wang XD*, Long-Term Quantitatively Imaging Intracellular Chloride Concentration Using a Core-/Shell-Structured Nanosensor and Time-Domain Dual-Lifetime Referencing Method. ACS Sensors 2020, 5(12):3971-3978. doi:10.1021/acssensors.0c01671

9. Ding WF^#*, Ma YY, Zhu WF, Pu WL, Zhou XD*, MICA *012:01 Allele Facilitates the Metastasis of KRAS-Mutant Colorectal Cancer. Frontiers in Genetics 2020, 11:511. doi:10.3389/fgene.2020.00511

10. Ekheden I^#, Yang XR^#, Chen H, Chen XD, Yuan ZY, Jin L, Lu M*, Ye WM*, Associations between Gastric Atrophy and Its Interaction with Poor Oral Health and the Risk for Esophageal Squamous Cell Carcinoma in a High-Risk Region of China: A Population-Based Case-Control Study. American Journal of Epidemiology 2020, 189(9):931-941. doi:10.1093/aje/kwz283

11. Fan JH^#, Liu ZQ^#, Mao XH, Tong X, Zhang TJ, Suo C^#*, Chen XD^#*, Global Trends in the Incidence and Mortality of Esophageal Cancer from 1990 to 2017. Cancer Medicine 2020, 9(18):6875–6887. doi:10.1002/cam4.3338

12. Gong TQ^#, Zhang CC^#, Ni XT^#, Li XJ, Li JE, Liu MW, Zhan DD, Xia X, Song L, Zhou Q, Ding C, Qin J, Wang Y*, A Time-Resolved Multi-omic Atlas of the Developing Mouse Liver. Genome Research 2020, 30(2):263-275. doi:10.1101/gr.253328.119

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14. Hou ZR^#, Wang XF, Wang YC, Wang JC*, Zhong J*, Association of Depressive Symptoms with Decline of Cognitive Function-Rugao Longevity and Ageing Study. Neurological Sciences 2020, 41(7):1873-1879. doi:10.1007/s10072-020-04279-8

15. Hu CY^#, Liu ZQ^#, Jiang YF^#, Shi OM^#, Zhang X^#, Xu KL, Suo C, Wang Q, Song YJ, Yu KK, Mao XH, Wu XF, Wu MS, Shi TT, Jiang W, Mu LN, Tully DC, Xu L, Jin L, Li SS, Tao XJ, Zhang TJ, Chen XD*, Early Prediction of Mortality Risk among Patients with Severe COVID-19, Using Machine Learning. International Journal of Epidemiology 2020, 49(6):1918-1929. doi:10.1093/ije/dyaa171

16. Hu ZX^#, Jiao R, Wang PP, Zhu Y, Zhao JY, De Jager P, Bennett DA, Jin L, Xiong MM*, Shared Causal Paths Underlying Alzheimer's Dementia and Type 2 Diabetes. Scientific Reports 2020, 10(1):4107. doi:10.1038/s41598-020-60682-3

17. Huang Y^#, Wang HY, Hao YZ, Lin HL, Dong MH, Ye J, Song L, Wang YZ, Li QQ, Shan BJ, Jiang YZ, Li HQ, Shao ZM, Kroemer G, Zhang HF, Bai L, Jin TC, Wang C, Ma YT, Cai YP, Ding C, Liu SL*, Pan YY*, Jiang W*, Zhou RB*, Myeloid PTEN Promotes Chemotherapy-Induced NLRP3-Inflammasome Activation and Antitumour Immunity. Nature Cell Biology 2020, 22(6):716-727. doi:10.1038/s41556-020-0510-3

18. Jiang YF^#, Lu HY^#, Man QH^#, Liu ZQ, Wang LP, Wang YZ, Suo C, Zhang TJ, Jin L, Dong Q, Cui M*, Chen XD*, Stroke Burden and Mortality Attributable to Ambient Fine Particulate Matter Pollution in 195 Countries and Territories and Trend Analysis from 1990 to 2017. Environmental Research 2020, 184:109327. doi:10.1016/j.envres.2020.109327

19. Jiang YF^#, Man QH^#, Liu ZQ, Wang YZ, Suo C, Jin L, Dong Q, Cui M*, Chen XD*, Temporal Trends in the Mortality Rate of Alzheimer's Disease and Other Dementias Attributable to Smoking, 1990–2017. Environmental Research 2020, 184:109183. doi:10.1016/j.envres.2020.109183

20. Jiang YF^#, Zhang KX^#, Zhu Z, Cui M, An YP, Wang YZ, Suo C, Fan M, Jin L, Tian WZ*, Chen XD*, Associations between Serum Metabolites and Subclinical Atherosclerosis in a Chinese Population: The Taizhou Imaging Study. Aging-US 2020, 12(15):15302-15313. doi:10.18632/aging.103456

21. Kong HJ^#, Chen B, Zhang XD, Wang CY, Yang M, Yang L, Wang XY, Zhang J*, Quantitative Renal Function Assessment of Atheroembolic Renal Disease Using View-Shared Compressed Sensing Based Dynamic-Contrast Enhanced MR Imaging: An In Vivo Study. Magnetic Resonance Imaging 2020, 65:67-74. doi:10.1016/j.mri.2019.10.007

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23. Li PX^#, Wang YZ^#, Jiang YF, Zhang KX, Yang Q, Yuan ZY, Zhu Z, Tang WJ, Fan M, Ye WM, Dong Q, Jin L, Ding D, Cui M*, Chen XD*, Cerebral Small Vessel Disease is Associated with Gait Disturbance among Community-Dwelling Elderly Individuals: the Taizhou Imaging Study. Aging-US 2020, 12(3):2814-2824. doi:10.18632/aging.102779

24. Lin Y^#, Zhang HH, Niu T, Tang ML*, Chang J*, Discovery of Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) and Histone Deacetylase 1 (HDAC1) Dual Inhibitors Derived from the Natural Product Saprorthoquinone. Molecules 2020, 25(19):4494. doi:10.3390/molecules25194494

25. Liu J^#, Wan W^#, Qiao YH^#, Li Y^#, Liu QM, Zhu Q, Yang CD, Zou YH, Ma YY, Zhou XD, Reveille JD, Jin L, Zou HJ, Wang JC*, A Rare Variant of RNF123 in Familial Ankylosing Spondylitis Causes Dysfunction of Osteoclast Formation. Rheumatology 2020, 59(5):1174-1177. doi:10.1093/rheumatology/kez537

26. Liu Q^#, Lin J^#, Han J^#, Zhang Y, Lu J, Tu W, Zhao Y, Guo G, Chu H, Pu W, Liu J, Ma Y, Chen X, Zhang R, Gu J, Zou H, Jin L, Wu W, Ren S, Wang JC*, Immunoglobulin G Galactosylation Levels are Decreased in Systemic Sclerosis Patients and Differ According to Disease Subclassification. Scandinavian Journal of Rheumatology 2020, 49(2):146-153. doi:10.1080/03009742.2019.1641615

27. Liu ZQ^#, Lin CQ, Mu LN, Suo C, Ye WM, Jin L, Franceschi S, Zhang TJ*, Chen XD*, The Disparities in Gastrointestinal Cancer Incidence among Chinese Populations in Shanghai Compared to Chinese Immigrants and Indigenous Non-Hispanic White Populations in Los Angeles, USA. International Journal of Cancer 2020, 146(2):329-340. doi:10.1002/ijc.32251

28. Liu ZQ^#, Mao XH^#, Yu KK, Suo C, Jin L, Zhang TJ*, Chen XD*, Prevalence of HCV Resistance-Associated Substitutions among Treatment-Failure Patients Receiving Direct-Acting Antiviral Agents. Journal of Viral Hepatitis 2020, 27(6):585-592. doi:10.1111/jvh.13270

29. Liu ZQ^#, Mao XH, Jin L, Zhang TJ*, Chen XD*, Global Burden of Liver Cancer and Cirrhosis among Children, Adolescents, and Young Adults. Digestive and Liver Disease 2020, 52(2):240-243. doi:10.1016/j.dld.2019.11.001

30. Liu ZQ^#, Suo C^#, Mao XH, Jiang YF, Jin L, Zhang TJ*, Chen XD*, Global Incidence Trends in Primary Liver Cancer by Age at Diagnosis, Sex, Region, and Etiology, 1990-2017. Cancer 2020, 126(10):2267-2278. doi:10.1186/s12974-020-1705-z

31. Long F^#, Wang Q, Yang D, Zhu ML, Wang JH, Zhu YZ, Liu XH*, Targeting JMJD3 Histone Demethylase Mediates Cardiac Fibrosis and Cardiac Function Following Myocardial Infarction. Biochemical and Biophysical Research Communications 2020, 528(4):671-677. doi:10.1016/j.bbrc.2020.05.115

32. Lv J^#, Wang P, Tong XR, Wang CY*, Parallel Imaging with a Combination of Sensitivity Encoding and Generative Adversarial Networks. Quantitative Imaging in Medicine and Surgery 2020, 10(12):2260-2273. doi:10.21037/qims-20-518

33. Ma T^#, Sun XH^#, Yao S, Chen ZK, Zhang JF, Xu WD, Jiang XY*, Wang XF*, Genetic Variants of Homocysteine Metabolism, Homocysteine, and Frailty-Rugao Longevity and Ageing Study. Journal of Nutrition Health & Aging 2020, 24(2):198-204. doi:10.1007/s12603-019-1304-9

34. Mei XQ^#, Zhao H, Huang Y, Tang YL, Shi XG, Pu WL, Jiang S, Ma YY, Zhang YT, Bai L, Tu WZ, Zhao YH, Jin L, Wu WY*, Wang JC*, Liu QM*, Involvement of Disabled-2 on Skin Fibrosis in Systemic Sclerosis. Journal of Dermatological Science 2020, 99(1):44-52. doi:10.1016/j.jdermsci.2020.05.009

35. Mei ZD^#, Dong X^#, Qian Y^#, Hong D, Xie ZA, Yao GF, Qin A, Gao SY, Hu JY, Liang LM*, Zheng Y*, Su JC*, Association between the Metabolome and Bone Mineral Density in a Chinese Population. EBioMedicine 2020, 62:103111. doi:10.1016/j.ebiom.2020.103111

36. Molina-Mora JA^#*, Campos-Sanchez R, Rodriguez C, Shi LM, Garcia F, High Quality 3C De Novo Assembly and Annotation of a Multidrug Resistant ST-111 Pseudomonas Aeruginosa Genome: Benchmark of Hybrid and Non-hybrid Assemblers. Scientific Reports 2020, 10(1):1392. doi:10.1038/s41598-020-58319-6

37. Molina-Mora JA^#*, Chinchilla-Montero D, Chavarria-Azofeifa M, Ulloa-Morales AJ, Campos-Sanchez R, Mora-Rodriguez R, Shi LM, Garcia F, Transcriptomic Determinants of the Response of ST-111 Pseudomonas Aeruginosa AG1 to Ciprofloxacin Identified by a Top-Down Systems Biology Approach. Scientific Reports 2020, 10(1):13717. doi:10.1038/s41598-020-70581-2

38. Qin Y^#, Kang JJ^#, Jiao ZY, Wang Y, Wang JC, Wang HY, Feng JF, Jin L, Wang F, Gong XH*, Polygenic Risk for Autism Spectrum Disorder Affects Left Amygdala Activity and Negative Emotion in Schizophrenia. Translational Psychiatry 2020, 10(1):322. doi:10.1038/s41398-020-01001-2

39. Sun DY^#, Yao S^#, Wu F, Deng W, Ma YY, Jin L*, Wang JC*, Wang XF*, Mitochondrial DNA Haplogroup M7 Confers Disability in a Chinese Aging Population. Frontiers in Genetics 2020, 11:577795. doi:10.3389/fgene.2020.577795

40. Sun XH^#, Ma T^#, Yao S, Chen ZK, Xu WD, Jiang XY*, Wang XF*, Associations of Sleep Quality and Sleep Duration with Frailty and Pre-frailty in an Elderly Population Rugao Longevity and Ageing Study. BMC Geriatrics 2020, 20(1):9. doi:10.1186/s12877-019-1407-5

41. Wang CY^#, Liang YC, Wu Y, Zhao SW, Du YP*, Correction of Out-of-FOV Motion Artifacts Using Convolutional Neural Network. Magnetic Resonance Imaging 2020, 71: 93-102. doi:10.1016/j.mri.2020.05.004

42. Wang JJ^#, Zhang YT^#, Zhuo Q^#, Tseng Y, Wang JC, Ma YY*, Zhang J*, Liu J*, TET1 Promotes Fatty Acid Oxidation and Inhibits NAFLD Progression by Hydroxymethylation of PPAR Alpha Promoter. Nutrition & Metabolism 2020, 17(1):46. doi:10.1186/s12986-020-00466-8

43. Wang XL^#, Xue JY^#, Zhang YY, Xie H, Wang YQ, Weng WY, Kang Y*, Huang JM*, DNA Barcodes for the Identifcation of Stephania (Menispermaceae) Species. Molecular Biology Reports 2020, 47(3):2197-2203. doi:10.1007/s11033-020-05325-6

44. Wang YL^#, Wu XY^#, An YP, Xie H, Hao FH, Tang HR*, Quantitative Metabonomic Phenotypes in Different Structures of Mung Bean (Vigna Radiata) Seeds and Their Germination-Associated Dynamic Changes. Journal of Proteome Research 2020, 19(8):3352-3363. doi:10.1021/acs.jproteome.0c00236

45. Wu JF^#*, Zhu XH, Lin H, Chen ZL, Tang HR, Wang YL*, Gender Differences in the Bile Acid Profiles of APP/PS1 Transgenic AD Mice. Brain Research Bulletin 2020, 161:116-126. doi:10.1016/j.brainresbull.2020.05.003

46. Wu XY^#, Wang YL^#, Tang HR*, Quantitative Metabonomic Analysis Reveals the Germination- Associated Dynamic and Systemic Biochemical Changes for Mung-Bean (Vigna Radiata) Seeds. Journal of Proteome Research 2020, 19(6):2457-2470. doi:10.1021/acs.jproteome.0c00181

47. Yang D^#, Wang Q, Wei G, Wu JX, Zhu YC, Zhu Q, Ni T*, Liu XH*, Zhu YZ*, Smyd3-PARP16 Axis Accelerates Unfolded Protein Response and Vascular Aging. Aging-US 2020, 12(21):21423-21445. doi:10.18632/aging.103895

48. Yang D^#, Wei G^#, Long F, Nie HB, Tian XL, Qu LF, Wang SX, Li P, Qiu Y, Wang Y, Hong WJ, Ni T*, Liu XH*, Zhu YZ*, Histone Methyltransferase Smyd3 is a New Regulator for Vascular Senescence. Aging Cell 2020, 19(9):e13212. doi:10.1111/acel.13212

49. Yang JC^#, Shang J^#, Song Q^#, Yang ZY, Chen JN, Yu Y*, Shi LM*, ECCDIA: An Interactive Web Tool for the Comprehensive Analysis of Clinical and Survival Data of Esophageal Cancer Patients. BMC Cancer 2020, 20(1):985. doi:10.1186/s12885-020-07479-9

50. Yang YT^#, De J^#, Fu ZL, Wang XL, Chen DF, Xie H*, Lu Y*, Molecular Identification Based on Chloroplast Sequences and Anti-complementary Activity Comparison of Juniperus Samples from the Qinghai-Tibet Plateau. Planta Medica 2020, 86(16):1176-1184. doi:10.1055/a-1194-0471

51. Yao S^#, Zhu YS, Shi GP, Guo JH, Wang ZD, Chu XF, Jiang XY, Jin L*, Wang XF*, Associations of TNF-α -308 G>A and TNF-β 252 A>G with Physical Function and BNP-Rugao Longevity and Ageing Study. Journal of Nutrition Health & Aging 2020, 24(3):358–363. doi:10.1007/s12603-020-1336-1

52. Yin CY^#, Su KY^#, He ZW, Zhai D, Guo KJ, Chen XY, Jin L*, Li SL*, Genetic Reconstruction and Forensic Analysis of Chinese Shandong and Yunnan Han Populations by Co-analyzing Y Chromosomal STRs and SNPs. Genes 2020, 11(7):743. doi:10.3390/genes11070743

53. Yin Q^#, Wang HY^#, Li N^#, Ding YF^#, Xie ZF^#, Jin LF^#, Li Y, Wang Q, Liu XY, Xu LQ, Li Q, Ma YJ, Cheng YB, Wang K, Zhong CQ, Yu Q, Tang W, Chen WJ, Yang WJ, Zhang F, Ding C, Bao L, Zhou B, Hu P*, Li JS*, Dosage Effect of Multiple Genes Accounts for Multisystem Disorder of Myotonic Dystrophy Type 1. Cell Research 2020, 30(2):133-145. doi:10.1038/s41422-019-0264-2

54. Zhang BH^#, Wang CY^#, Wang HC, Kong HJ, Gao F, Yang M*, Zhang J*, Feasibility of MRI Based Oxygenation Imaging for the Assessment of Acute Limb Ischemia. Annals of Translational Medicine 2020, 8(6):315. doi:10.21037/atm.2020.02.139

55. Zhang F^#, Yang B, Wang YZ, Zhu JJ, Liu J, Yu GY, Qin J, Song WM*, Ding C*, Time-and Dose-Resolved Proteome of PM2.5-Exposure-Induced Lung Injury and Repair in Rats. Journal of Proteome Research 2020, 19(8):3162-3175. doi:10.1021/acs.jproteome.0c00155

56. Zhang HR^#, Li YT^#, Guo SC, Wang Y, Wang HJ, Lu DR, Wang JC, Jin L, Jiang GX, Wu JJ*, Han YP*, Li JH*, Effect of ERCC2 rs13181 and rs1799793 Polymorphisms and Environmental Factors on the Prognosis of Patients with Lung Cancer. American Journal of Translational Research 2020, 12(10):6941-6953.

57. Zhang KX^#, Jiang YF^#, Wang YZ, Suo C, Xu KL, Zhu Z, Zhu CK, Zhao GM, Jin L, Ye WM, Cui M*, Chen XD, Associations of Arterial Stiffness and Carotid Atherosclerosis with Cerebral Small Vessel Disease in a Rural Community-Based Population. Journal of Atherosclerosis and Thrombosis 2020, 27(9):922-933. doi:10.5551/jat.52530

58. Zhang YY^#, Kang Y, Xie H, Wang YQ, Li YT, Huang JM*, Comparative Transcriptome Analysis Reveals Candidate Genes Involved in Isoquinoline Alkaloid Biosynthesis in Stephania Tetrandra. Planta Medica 2020, 86(17):1258-1268. doi:10.1055/a-1209-3407

59. Zheng YF^#, Cui BP^#, Sun WR, Wang SN, Huang X, Gao H, Gao F, Cheng Q, Lu LM, An YP, Li XB*, Sun N*, Potential Crosstalk between Liver and Extra-Liver Organs in Mouse Models of Acute Liver Injury. International Journal of Biological Sciences 2020, 16(7):1166-1179. doi:10.7150/i j bs.41293

60. Zhou YJ^#, He FA, Pu WL, Gu X, Wang JC*, Su ZX*, The Impact of DNA Methylation Dynamics on the Mutation Rate During Human Germline Development. G3-Genes Genomes Genetics 2020, 10(9):3337-3346. doi:10.1534/g3.120.401511

61. Zhu SB^#, Jiang YF, Xu KL, Cui M, Ye WM, Zhao GM, Jin L, Chen XD*, The Progress of Gut Microbiome Research Related to Brain Disorders. Journal of Neuroinflammation 2020, 17(1):25. doi:10.1186/s12974-020-1705-z

62. Zhu Z^#, Jiang YF^#, Cui M, Wang YZ, Li SY, Xu KL, Zhang KX, Zhu CK, Xu WH, Jin L, Ye WM, Suo C, Chen XD*, ALDH2 rs671 Polymorphisms and the Risk of Cerebral Microbleeds in Chinese Elderly: the Taizhou Imaging Study. Annals of Translational Medicine 2020, 8(5):229. doi:10.21037/atm.2020.01.01