工作经历
2009年毕业于中国药科大学药物代谢动力学专业。同年进入复旦大学药学院工作，综合利用细胞模型、分子功能试验、RNA-seq等研究手段，研究药物个性化反应标志物。2016年转入复旦大学生命科学学院，致力于建立基于组学标准物质的性能验证与质量控制方法，促进高通量组学技术在药物研发中的应用。
作为国家重点研发计划课题负责人和项目协调人，研制了国际首例多组学标准物质与标准数据集，在业界得到较为广泛的应用。主持和参与国家重点研发计划课题、国家863计划课题、国家自然科学基金、企业合作项目等10项；发表SCI论文40余篇，SCI引用1000余次；申请国家发明专利9项，授权4项；共同主编《大数据与精准医学》一书。
研究方向
药物基因组学
招生专业
遗传学（人类和医学分子遗传学）
代表论文
1.Li WR, Guo LL, Xing ZK, Fang X, Liang H, Zhang SN, Shi L, Kuang CX, Shi LM, Zheng YT#, Hu YQ#, Yang Q#. Forty-three key gene expressions involved in the effect of indoleamine 2,3-dioxygenase 1 expression on cancer prognosis may be a potential indoleamine 2,3‐dioxygenase 1 inhibitor biomarker. Clin Transl Med. 2021; e330.
2.Chen YM#, Zheng Y#, Yu Y#, Wang Y#, Huang Q#, Qian F#, Sun L#, Song ZG, Chen Z, Feng J, An Y, Yang J, Su Z, Sun S, Dai F, Chen Q, Lu Q, Li P, Ling Y, Yang Z, Tang H, Shi L, Jin L, Holmes EC, Ding C, Zhu TY, Zhang YZ. Blood molecular markers associated with COVID-19 immunopathology and multi-organ damage. EMBO J. 2020; e105896.
3.Chen H, Carrot-Zhang J, Zhao Y, Hu H, Freeman SS, Yu S, Ha G, Taylor AM, Berger AC, Westlake L, Zheng Y, Zhang J, Ramachandran A, Zheng Q, Pan Y, Zheng D, Zheng S, Cheng C, Kuang M, Zhou X, Zhang Y, Li H, Ye T, Ma Y, Gao Z, Tao X, Han H, Shang J, Yu Y, Bao D, Huang Y, Li X, Zhang Y, Xiang J, Sun Y, Li Y, Cherniack AD, Campbell JD, Shi L, Meyerson M. Genomic and immune profiling of pre-invasive lung adenocarcinoma. Nature Communications. 2019; 10 (1): 5472.
4.Jiang YZ, Ma D, Suo C, Shi J, Xue M, Hu X, Xiao Y, Yu KD, Liu YR, Yu Y, Zheng Y, Li X, Zhang C, Hu P, Zhang J, Hua Q, Zhang J, Hou W, Ren L, Bao D, Li B, Yang J, Yao L, Zuo WJ, Zhao S, Gong Y, Ren YX, Zhao YX, Yang YS, Niu Z, Cao ZG, Stover DG, Verschraegen C, Kaklamani V, Daemen A, Benson JR, Takabe K, Bai F, Li DQ, Wang P, Shi L, Huang W, Shao ZM. Genomic and transcriptomic landscape of triple-negative breast cancers: subtypes and treatment strategies. Cancer Cell. 2019; 35(3): 428-440.e5.
5.Yu Y, Wang Y, Xia Z, Zhang X, Jin K, Yang J, Ren L, Zhou Z, Yu D, Qing T, Zhang C, Jin L, Zheng Y#, Guo L#, Shi L. PreMedKB: an integrated precision medicine knowledgebase for interpreting relationships between diseases, genes, variants and drugs. Nucleic Acids Research. 2019; 47(D1): D1090-D1101.
6.Qing T, Zhu S, Suo C, Zhang L, Zheng Y#, Shi L#. Somatic mutations in ZFHX4 gene are associated with poor overall survival of Chinese esophageal squamous cell carcinoma patients. Scientific Reports. 2017; 7(1): 4951.
7.Li B, Qing T, Zhu J, Wen Z, Yu Y, Fukumura R, Zheng Y#, Gondo Y#, Shi L#. A Comprehensive Mouse Transcriptomic BodyMap across 17 Tissues by RNA-seq. Scientific Reports. 2017; 7(1): 4200.
